Übertroffen

Ich hatte 3 : 1 gegen Argentinien getippt...

Das 4 : 0 übertrifft natürlich alle Erwartungen, da reicht das höchste Lob eines Franken "Passt schoo" gar nicht mehr aus!

Knoblauch gegen Krebs

Researchers have discovered that mincing your garlic and letting it sit uncovered at room temperature for 10–15 minutes before cooking it will activate its cancer-fighting phytochemicals.

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Differentialdiagnose des Asthmas

A 10-year-old previously healthy girl presented with episodic wheezing, dyspnea, and progressive exercise intolerance, which had developed during the preceding 9 months. On physical examination, the patient had moderate bilateral expiratory wheezing. She was treated for presumed asthma with multiple courses of inhaled bronchodilators, inhaled corticosteroids, montelukast, and oral corticosteroids. Though the patient reported that her condition had improved somewhat, there was no demonstrable objective improvement. Further evaluation by spirometry revealed severe expiratory obstruction (Panel A). The patient underwent flexible fiberoptic bronchoscopy, which revealed nearly complete (>90%) occlusion of the distal trachea by a vascular mass. Computed tomographic angiography showed that the mass did not extend beyond the trachea (Panel B, arrow). The mass was ablated endoscopically with the use of a potassium titanyl phosphate laser. Pathological analysis revealed an inflammatory pseudotumor, a benign tumor composed of a proliferation of inflammatory cells. Rarely invasive, this type of tumor is usually cured by local excision. One month after surgery, the patient was free of symptoms and had normal results on spirometry (Panel C). Pulmonary pseudotumors are rarely the cause of wheezing. However, a lack of response to first-line therapies warrants further investigation, including spirographic analysis.

NEJM Volume 363:e1 July 1, 2020 Number 1

Lungenembolie

The clinical presentation of acute pulmonary embolism ranges from shock or sustained hypotension to mild dyspnea. Pulmonary embolism may even be asymptomatic and diagnosed by imaging procedures performed for other purposes. Depending on the clinical presentation, the case fatality rate for acute pulmonary embolism ranges from about 60% to less than 1%.1 Anticoagulation is the foundation of therapy for pulmonary embolism. Depending on the estimated risk of an adverse outcome, admission to an intensive care unit and treatment with thrombolysis or catheter or surgical embolectomy may be required, but early hospital discharge or even home treatment may be considered. This review focuses on the optimal diagnostic strategy and management, according to the clinical presentation and estimated risk of an adverse outcome.

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